Contents
Cal Poly Pomona

Conference Agenda

NUTRITIONAL GENOMICS CONFERENCE:
The Impact of Dietary Regulation of Gene Function on Human Disease

Thursday, November 12, 2009

  • 7:30 AM: Registration & Continental Breakfast
  • 8:15 AM: Welcome and Introduction to Conference
    Wayne R. Bidlack, Ph.D.
    Organizer, Professor Human Nutrition and Food Science, Cal Poly Pomona, CA

Theme I: Transforming Dietary Signals into Disease-Preventing Changes in Gene Expression

Session I.1 Wayne Bidlack, PhD, Session Chair

  • Plenary Speaker
  • 8:30 AM: Using the “Omics” of Nutrition to Identify Molecular Targets
    Sharon Ross, Ph.D., MPH.
    Program Director, Nutritional Science Research Group,
    Division of Cancer Prevention, NIH/NCI, Bethesda, MD
  • 9:30 AM: Epigenomics in Diabetes, Metabolic Memory and Their Inflammatory Complications
    Rama Natarajan, Ph.D.
    Professor, Department of Diabetes and Metabolic Diseases Research,
    Division Endocrinology and Metabolism, Beckman Research Institute City of Hope, Duarte, CA
  • 10:15 AM: Break
  • 10:30 AM: Diet-Informed Epigenetic Modulation: Reprogramming the Epigenome to Express Chemopreventive Genes
    Raymond Rodriguez, Ph.D.
    Molecular and Cellular Biology and Director,
    Center of Excellence in Nutritional Genomics, UC Davis, Davis, CA
  • 11:15 AM: Understanding Diet x Genome Interactions in Complex Systems: a Systems Biology Approach
    Jun Zhu, Ph.D.
    Director, Sage Bionetwork, Seattle, WA
  • 12:00 PM: Lunch

Session I.2 Raymond Rodriguez, PhD, Session Chair

  • 1:00 PM: Modulation of Atherosclerosis by Omega-3 Polyunsaturated Fatty Acids
    Darshan Kelley, Ph.D.
    WHNRC/Immunity and Disease Prevention Research Unit ARS, USDA and Department of Nutrition,
    UC Davis, CA
  • 1:45: Analysis of ω-3 Fatty Acids-Responsive Gene Expression and Pathways
    Kevin Dawson, Ph.D.
    Chief Infomatics Scientist, Bioinfomatics Research Core, Center of Excellence in Nutritional Genomics, UC Davis, Davis, CA
  • 2:30 PM: Break
  • 3:00 PM: Nuclear Receptor Coactivators: Physiology, Metabolism and Disease
    David M. Lonard, Ph.D.
    Assistant Professor, Department of Molecular and Cellular Biology
    Baylor College of Medicine, Houston, TX
  • 3:45: To D or Not to D: Vitamin D and Cardiovascular Disease
    Keith C. Norris, MD,
    FACP Program Director for Clinical Research Center & Comprehensive Center for Health Disparities in Chronic Kidney Disease, Charles Drew University of Medicine and Science, Lynwood CA
  • 4:30 PM: Closing
  • 4:45 PM: Registered Dietitians and Dietetic/Nutrition Students Discussion of Nutritional Genomics

Friday, November 13, 2009

  • 8:00 AM: Continental Breakfast
  • 8:25 AM: Introduction

Theme II: Gene Linked Networks of Chronic Disease and Cancer

Session II.1 Gale Strasburg, Ph.D, Session Chair

  • 8:30 AM: The Genetics of Metabolic Syndrome as it Relates to T2DM and Obesity
    Margarita Teran-Garcia, M.D., Ph.D.
    Assistant Professor, Department of Food Sciences and Human Nutrition,
    University of Illinois at Urbana-Champaign, Il
  • 9:15 AM: Nutrigenomics of Fatty Acid Sensing: Role of PPARs
    Sander Kersten, Ph.D.
    Associate Professor, Nutrition, Metabolism and Genomics Group, Division of Human Nutrition,
    Wageningen University, The Netherlands
  • 10:00 AM: Break
  • 10:15 AM: Effects of Dietary Effectors on Signal Transduction Pathways Related to Cancer Prevention
    Zigang Dong, MD, DPH Professor and Executive Director, Cancer Prevention,
    Hormel Institute, University Minnesota, Austin, MN
  • 11:00 AM: Skin Cancer Chemoprevention by Green Tea Polyphenols
    Santosh Kumar Katiyar, Ph.D.
    Associate Professor of Dermatology, University Alabama, Birmingham, Al 35294
  • 11:45 AM: Lunch

Session II.2 Stella Cash, MEd, MS, RD, Session Chair

  • Plenary Speaker
  • 12:30 PM Bioactive Food Components and the “U” Shaped Health Conundrum:
    Vitamin D and Folate as Examples of Friends and Foes

    John Milner, Ph.D.
    Chief Nutritional Science Research Group, Division of Cancer Prevention, NCI/NIH, Bethesda, MD
  • 1:30 PM: Insulin Resistance and T2DM: Adipose Tissue Macrophage and Inflammation
    Jerrold M. Olefsky, MD
    Associate Dean Scientific Affairs and Chief, Division Endocrinology and Metabolism,
    UCSD, La Jolla, CA
  • 2:15 PM Network Analysis of Gene Expression in Breast Cancer Cells
    T. Gregory Dewey, Ph.D.
    Finnigan Professor of Applied Life Sciences,
    Keck Graduate Institute, Claremont, CA
  • 3:00 PM: Break
  • 3:15 PM: Human Intestinal Microbiome: Etiology of Inflammation Genomics
    Roger A. Clemens, DPH
    Associate Director, Regulatory Science Program Adjunct Professor,
    Department Pharmacology and Pharmaceutical Sciences School of Pharmacy,
    University of Southern California, Los Angeles
  • 4:00 PM: The Gut Brain Connection: personalized Genomics and Nutrition Therapy
    Colleen Fogarty Draper, MS, RD
    President/Founder, Integrative Nutrition Therapist, Nugenso Company, Boston, MA
  • 4:45 PM: Closing
  • 5:00 PM: Reception Hors d’oeuveres and open bar

Saturday, November 14, 2009

  • 8:00 AM: Continental Breakfast
  • 8:25 AM: Introduction

Theme III: Role of Food Science and Nutrition to Meet Individual Genomic Health Needs

Session III.1 David W. Still, Ph.D., Joseph Baur, Ph.D., Session Co-Chairs

  • 8:30 AM: Calcium Biofortification of Crops
    Kendal D. Hirschi, Ph.D.
    Professor, Department Pediatrics, Nutrition and Human & Molecular Genetics,
    Baylor College of Medicine, CNRC, Houston, TX,
    and Professor, Molecular and Environmental Plant Sciences, and Associate Director, Vegetable and Fruit Improvement Center, Texas A&M University, College Station Texas
  • 9:15 AM: Using Genomics-aided Breeding to Improve Nutritional Content of Lettuce
    David W. Still, Ph.D.
    Campus Coordinator, Agricultural Research Initiative, and Professor Plant Sciences
    California State Polytechnic University, Pomona, CA
  • 10:00 AM: Break
  • 10:15 AM: Natural Colorants as Bioactive Agents in Functional Foods
    Anne Marie Craig, Ph.D.
    Assistant Professor, Food Chemistry Analysis, Department Human Nutrition and Food Sciences
    California State Polytechnic University, Pomona, CA
  • 11:00 AM: Resveratrol Alters Global Patterns of Gene Regulation and Improves Physiology
    Joseph Baur, Ph.D.
    Institute for Diabetes, Obesity and Metabolism, Department of Physiology
    University of Pennsylvania School of Medicine, Philadelphia, PA
  • 11:45 AM: Lunch

Session III.2 Gilbert Leville, Ph.D, Session Chair

  • 12:30 AM: Cocoa Extract Supplementation: Formulation Challenges and Measurement of Bioactives
    Mary Wagner, Ph.D.
    General Manager and Chief Technology Officer for Mars Botanical, Rockville, MD
  • 1:15 PM: Manufacturing Functional Foods: Effects on Quality and Bioavailability
    John Floros, Ph.D.
    Professor and Head, Department of Food Science,
    Pennsylvania State University, University Park, PA
  • 2:00 PM: New Whole Foods Designed to Deliver Bioactive Components
    Cheryl Mitchell, Ph.D.
    President and Senior Research Chemist, Creative Research Management, Stockton, CA
  • 2:45 PM: Break
  • 3:00 PM: Nutritional Genomics and the Future of Food Labeling
    Evelyn Cadman
    Owner and Principal Consultant, Biosciences Translation & Applications,
    Colorado
  • 3:45 PM: Panel Discussion: Future Potential for Nutritional Genomic Products
    Gilbert Leveille, Ph.D., Moderator
    Leveille Associates, Scientific and Regulatory Consulting Services to Food Industry
  • Panel Members
    • Wayne R. Bidlack, Ph.D. Professor, Dept Human Nutrition and Food Science, Cal Poly Pomona
    • Raymond Rodriguez, Ph.D., Director, Center for Excellence Nutritional Genomics, UC Davis, Davis, CA
    • Colleen F. Draper, MS, RD, LDN, President, Integrative Nutrigenomics, Nugenso Company, Boston, MA
  • 4:30 PM: Conclusion and Acknowledgements

Discussions throughout the program will assess the needs of Personalized Nutrition, targeting specific gene responses, identified after 10 years of research and development. Importantly, the conference concludes with a discussion of the future vision of nutritional genomics identifying research targets and consumer applications.

 

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Conference Themes

Thursday, November 12
Theme I: Transforming Dietary Signals into Disease-Preventing Changes in Gene Expression

Friday, November 13
Theme II: Gene Linked Networks of Chronic Disease and Cancer

Saturday, November 14
Theme III: Role of Food Science and Nutrition to Meet Individual Genomic Health Needs