BUCKLEY'S RESEARCH
Cannabinoid Research
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BUCKLEY'S RESEARCH |
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My Research deals with investigating the role of cannabinoids and cannabinoid receptors in the immune system. Marijuana components, such as delta-9-tetrahydrocannabinol (THC), and the endogenous cannabinoids arachidonoylethanolamine (anandamide) and 2-arachidonoylglycerol (2-AG) alter immune functions. Cannabinoids affect lymphocytes, macrophages and natural killer cells in a variety of functions. Overall, cannabinoids are perceived as immunosupressors, although this notion has been recently challenged, since some cannabinoids are known to enhance lymphocyte proliferation. |
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