Advisor |
Analytical Chemistry Research Interests |
| Dr. Hossein Ahmadzadeh |
The major research directions that I am interested in
are in the areas of bioanalytical, forensic and environmental chemistry.
Some examples of my research interest are:
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Instrumentation for Single cell and subcellular
Analysis: We are developing instrumentations for the “Analysis of
Single Cells” for diagnostic and prognostic purposes. The main focus
would be on the Application of Capillary Electrophoresis with LIF
detection.
-
Direct Sampling of Mitochondria from Tissue
Cross Sections: We have developed a sampling strategy that could
directly sample mitochondria from tissue cross sections. The
mitochondrial contents of individual fibers have been directly sampled
and analyzed.
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Environmental Chemistry: We are interested
in using Immunoassay techniques for the trace analysis of natural
toxins, such as microcystins produced by blue-green alga in natural
waters. Microcystins are liver carcinogens present in natural waters in
minute amounts. Capillary-format immunoassay techniques with LIF
detection is the best technique to monitor zeptomol amount of these
toxins in natural waters. We have used this approach both for the
analysis of natural toxins and monitoring explosive compounds in natural
waters.
-
Trace Element Analysis: We are interested in
the low ppb level of trace metal analysis in body fluids and in the
environment.
-
Fatty Acid Profiling of Biodiesel: We are
developing a separation method for the analysis of biodiesel fatty acid
contents produced from Chlorella protothecoides, Botryococcus
braunii, a local algae mixture, and other biomass sources
such as canola oil, sesame seed oil, and corn oil.
-
Analysis of E-coli: A capillary
electrophoresis separation strategy with Laser Induced Fluorescence
Detection for the analyses of E-coli bacteria is under investigation.
The main focus is on using silica nanoparticles (< 100 nm) to encapsulate the glycolipid Gb3 and/or the
monoclonal antibody receptors. The nanoparticles will be introduced to
meat and dairy products that have been contaminated with STEC, then
extracted and placed in a CE equipped with a sheath-flow cuvette LIF.
This procedure will provide the capability of detecting zepto mole (10-21
mol) levels of Stx in ground meat.
|
Dr. Fredrick Bet-Pera |
Trace Determination: In this investigation the primary concern will be developing highly
sensitive and selective methods for analyses of trace metals and nonmetals such
as arsenic, tellurium, selenium, germanium and cyanide. Most of the experimental
work will involve using atomic absorption and electrochemical instrumentation.
Methodology will be extended to determinations in natural waters as well as
synthetic samples.
Electrochemical Investigations:The major effort in
this category of research will be devoted to study the aqueous chemistry of some
transition metals such as vanadium, niobium, tungsten and uranium in different
oxidation states. The experimental work will involve using different electrochemical
techniques for identifying different transition metal species that are involved in the
electrochemical reduction.
The third area of investigation
is the occurrence of trace elements in human tissue.
Most of the experimental work will involve using
Anodic stripping voltammetry (ASV). |
Dr. Nelson Scott |
Environmental toxicology and bioanalytical chemistry.
Development of analytical methods for quantifying
trace levels of inorganic and organic toxins and
their metabolites in various biomatrices.
In vitro investigations of the mechanism(s) of
toxicity of environmental pollutants. |
Dr. George Gutnikov |
My research interests for Senior projects
(and graduate students) lie in the determination of
fatty acid profiles by capillary electrophoresis. |
